1. Increased uptake of FDG in tumor cells is due to:

a. Increased glucose transport into tumor cells

b. Up-regulation of hexokinase

c. Increased rates of glycolysis of tumor cells

d. All of the above

2. Which of the following statements is true?

a. Anatomic imaging detects structural abnormalities with a high accuracy.

b. Size criteria reliably characterize structural abnormalities as malignant or benign.

c. Anatomic imaging generally has a high specificity for characterizing these abnormalities mass lesions as malignant or benign.

d. PET accurately characterizes lesions smaller than 5 mm as malignant or benign.

3. Which of the following statements is true?

a. Molecular PET imaging with FDG differentiates benign from malignant lesions with a high accuracy

b. FDG-PET images provide exquisite anatomical detail

c. CT imaging is more specific for lesion characterization than FDG-PET

d. The accuracy of CT imaging for determining mediastinal lymph node involvement in lung cancer patients is greater than 90%

4. Which of the followng statements about PET and/or CT imaging is true?

a. CT imaging is superior to PET imaging for staging of mediastinal lymph nodes.

b. PET and CT images read side by side provide more accurate mediastinal staging information than CT and PET alone.

c. PET stages mediastinal lymph node involvement with an accuracy that is 15 ­20% lower than that of CT alone.

d. CT is the modality of choice for mediastinal lymph node staging.

5. Fusion of independently acquired PET and CT images is difficult because it is:

a. Time-consuming

b. Error-prone due to significantly different patient position

c. Misalignment of images due to respiratory motion

d. All of the above

6. The potential advantages of the LSO detector technology include:

a. Standard FDG doses can be injected

b. Images are acquired in the 3D mode

c. Whole-body PET/CT studies can be performed in 15 minutes or less

d. All of the above

7. The advantages of dual modality PET/CT imaging include:

a. Metabolic and anatomic whole body staging of patients can be performed in one examination

b. Because of limited patient motion near ideal fusion of metabolic and anatomic images can be achieved

c. PET/CT requires less time for image acquisition than PET alone

d. All of the above

8. PET/CT imaging will be most useful for:

a. Difficult to image regions of the body

b. Planning of radiation therapy

c. Monitoring of cancer treatment

d. All of the above

9. A PET/CT study requires more time for completion than:

a. Whole- body PET scan

b. CT scan

c. The FDG injection

d. All of the above

10. The correct sequence of events for a PET/CT imaging protocol is:

a. Topogram, CT, PET

b. CT, Topogram, PET

c. PET, Topogram, CT

d. Topogram, PET, CT