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The Sonographic Detection of Trisomy 13


1. The incidence of trisomy 13 is approximately:

a. 1:2000

b. 1:4000

c. 1:6000

d. 1:8000

e. 1:10,000



2. The median survival for a neonate with trisomy 13 is:

a. 12 hours

b. 8.5 days

c. 3.2 weeks

d. 1.4 months

e. 2 years



3. The presence of a mosaic placenta with trisomy 13 decreases the likelihood of survival to the neonatal period.

a. True

b. False



4. A bilateral cleft lip is pathognomonic for trisomy 13.

a. True

b. False



5. The 1st trimester fetal heart rate is > 95th centile for gestational age in over 50% of trisomy 13 fetuses.

a. True

b. False



6. A combination of maternal age and a nuchal translucency measurement will detect approximately 80% of trisomy 13 cases.

a. True

b. False



7. The major congenital anomalies detected in the 1st trimester that have been associated with trisomy 13 include all of the following, except:

a. Holoprosencephaly

b. Omphalocele

c. Megacystis

d. Clubbed foot



8. First trimester serum PAPP-A is increased with trisomy 13.

a. True

b. False



9. A major congenital anomaly can be detected on an extended 2nd trimester ultrasound examination in ________% of trisomy 13 cases:

a. 40

b. 50

c. 60

d. 70



10. Soft 2nd trimester sonographic signs associated with trisomy 13 include all of the following, except:

a. Thickened nuchal fold

b. Echogenic small bowel

c. Echogenic intracardiac focus

d. Wide pelvic iliac angle

e. Shortened humerus





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